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Medchemexpress LLC CCT251455 | 1400284-80-1 | 99.1% | 503.98 | C26H26ClN7O2 | 10MG
Supplier: Medchemexpress LLC HY1260310MG
CCT251455 is a potent, selective inhibitor of mitotic kinase monopolar spindle 1 (MPS1) with an IC50 of 3 nM. It exhibits cellular potency (P-MPS1 IC50 ≈ 0.04 μM; GI50 ≈ 0.16 μM) and shows oral pharmacokinetic activity in mouse and rat, making it suitable for preclinical research into mitotic checkpoint signaling and anticancer mechanisms.
- Potent MPS1 inhibition, IC50 3 nM.
- Demonstrates cellular activity: P-MPS1 IC50 ≈ 0.04 μM and GI50 ≈ 0.16 μM.
- Shows oral pharmacokinetic activity in rodent models.
- High purity for biochemical and cellular assays.
- Available in multiple milligram quantities and as a DMSO solution.
- Storage recommendations provided for powder and solution to preserve stability.
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