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Medchemexpress LLC CCT369260 | 2647503-57-7 | >99.67% | 10 MG
Supplier: Medchemexpress LLC HY12918810MG
CCT369260 is a chemical probe and an orally active B-cell lymphoma 6 (BCL6) inhibitor with anti-tumor activity. It exhibits an IC50 of 520 nM. In an in vivo study, CCT369260 (15 mg/kg, orally, single dose) significantly inhibited BCL6 in an OCI-Ly1 DLBCL xenograft model in female SCID mice, leading to decreased levels of BCL6 in the tumor observed up to 10 hours after administration.
- Orally active B-cell lymphoma 6 (BCL6) inhibitor
- Demonstrates anti-tumor activity
- Exhibits an IC50 of 520 nM
- Significant inhibition of BCL6 in OCI-Ly1 DLBCL xenograft model
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