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Medchemexpress LLC CCT374705 | 2640647-90-9 | C21H18ClF3N4O2 | 100 MG

Supplier: Medchemexpress LLC HY153521100MG
CCT374705 is an orally active BCL6 inhibitor (IC50 = 4.8 nM) with potent antiproliferative effects in vitro. It effectively inhibits tumor growth in a lymphoma xenograft mouse model.
- Effectively inhibits tumor growth in a lymphoma xenograft mouse model.
- Good oral bioavailability.
- Low total clearance and plasma protein binding, leading to high free concentrations in Balb/C mice.
- Modulates BCL6 activity.
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