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Medchemexpress LLC CD161 Cynomolgus H 50ug | 50ug
Supplier: Medchemexpress LLC HYP7759250UG
CD161 Protein plays a crucial role in inhibiting NK cell cytotoxicity by activating specific acid sphingomyelinase/SMPD1 elevating ceramide levels Activation stimulates AKT1/PKB and RPS6KA1/RSK1 kinases enhancing anti-CD3-induced T-cell proliferation As a lectin CD161 binds to Gal-alpha(1 3)Gal and N-acetyllactosamine epitopes acting as a ligand for CLEC2D/LLT1 Existing as a homodimer CD161 interacts with acid sphingomyelinase/SMPD1 contributing to its multifaceted immune regulatory functions CD161 Protein Cynomolgus (HEK293 His) is the recombinant cynomolgus-derived CD161 protein expressed by HEK293 with C-His labeled tag
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