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Medchemexpress LLC CDK/HDAC-IN-3 | 2944087-54-9 | 99.60% | 509.34 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY14981950MG

Encompass_Preferred

CDK/HDAC-IN-3 is an orally active HDACs/CDKs dual inhibitor. It potently and selectively inhibits CDK9, CDK12, CDK13, HDAC1, HDAC2, and HDAC3. This compound can be used for acute myeloid leukemia (AML), significantly inducing differentiation of leukemic stem-like cells and inhibiting AML proliferation. It also demonstrates inhibitory effects on U937, HL-60, SKNO-1, and Kaumi-1 cells.

  • Potent and selective dual inhibition of HDACs/CDKs.
  • Inhibits CDK9, CDK12, CDK13, HDAC1, HDAC2, HDAC3.
  • Induces differentiation of leukemic stem-like cells.
  • Inhibits AML proliferation.
  • Effective against U937, HL-60, SKNO-1, and Kaumi-1 cells.
  • Demonstrates adequate oral bioavailability.

Catalog No. 50-003-61798


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