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Medchemexpress LLC CDK9-IN-2 | 1263369-28-3 | 98.7% | 425.93 | 5 MG
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Supplier:  Medchemexpress LLC HY164625MG

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CDK9-IN-2 is a special cyclin-dependent kinase 9 (CDK9) inhibitor, extracted from patent WO/2012131594A1, compound CDKI(8). It has an IC50 of 5 nM and 7 nM in H929 multiple myeloma (MM) cell line (72 hours) and A2058 skin cell line (72 hours), respectively. It is for research use only and not sold to patients.

  • Special cyclin-dependent kinase 9 (CDK9) inhibitor.
  • Extracted from patent WO/2012131594A1, compound CDKI(8).
  • IC50 of 5 nM in H929 multiple myeloma (MM) cell line (72 hours).
  • IC50 of 7 nM in A2058 skin cell line (72 hours).
  • Reduces expression of MEPCE.
  • Reduces MCL1 protein expression.
  • Appearance: solid, light yellow to yellow.
  • Effective in inhibiting CDK9 activity.
  • Has antiproliferative activity against various cell lines including 4T1, A498, A549, AD293, BT-549, HK-2, HeLa, HepG2, Hs-578T, L02, MCF-10A, MDA-MB-231, and MRC5.

Catalog No. 50-202-9201


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