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Medchemexpress LLC Ce-245677 | 717899-97-3 | 98.1% | 513.38 g/mol | C24H22Cl2N6O3 | 5 MG

Supplier: Medchemexpress LLC HY1124235MG
CE-245677 is a potent, reversible small-molecule inhibitor of Tie2 and TrkA/B receptor tyrosine kinases, developed for preclinical research. It shows low-nanomolar cellular potency and has been characterized for in vitro assays and in vivo pharmacokinetic studies; the compound is provided as a powder with documented solubility and storage conditions to support experimental use.
- Potent reversible inhibitor of Tie2 and TrkA/B with low-nanomolar cellular activity.
- High purity suitable for biochemical and cellular assays.
- Powder form with defined cold-storage recommendations.
- Readily soluble in DMSO; in vivo formulation guidance available.
- Demonstrated oral bioavailability in rodent pharmacokinetic studies.
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