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Selleck Chemical LLC Cediranib (AZD2171) 10mM/1mL 288383-20-0 NSC-732208
Supplier: Selleck Chemical LLC S101710MM/1ML
Cediranib (AZD2171, NSC-732208) is a highly potent VEGFR(KDR) inhibitor with IC50 of <1 nM, also inhibits Flt1/4 with IC50 of 5 nM/?3 nM, similar activity against c-Kit and PDGFR?, 36-, 110-fold and >1000-fold selective more for VEGFR than PDGFR-?, CSF-1R and Flt3 in HUVEC cells. Cediranib (AZD2171) induces autophagic vacuole accumulation. Phase 3. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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