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Apexbio Technology LLC Cefotaxime (sodium salt)(Synonyms: Claforan, Cefotaxime Sodium, Cefotaxim sodium salt, Cefotaxime Na, Sodium cefotaxime), 1g, CAS: 64485-93-4.
Supplier: Apexbio Technology LLC C45881000
Cefotaxime sodium (CAS 64485-93-4) is a third-generation cephalosporin antibiotic belonging to the -lactam group characterized by inhibition of bacterial cell-wall synthesis through binding to penicillin-binding proteins In vitro analyses show strong inhibitory efficacy against various bacterial species notably cefotaxime exhibits an MIC below 0 1 g/ml against Streptococcus pneumoniae It also demonstrates high activity against Haemophilus influenzae including -lactamase-producing strains In vivo mouse model studies revealed that combination therapy of cefotaxime with minocycline enhanced survival following Vibrio vulnificus infection compared to single-agent treatments Clinically cefotaxime has been evaluated in pneumonia therapy demonstrating good tolerance and therapeutic utility in targeting susceptible bacterial pathogens
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