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Medchemexpress LLC Ceftolozane sulfate | 936111-69-2 | 99.7% | 764.77 | 5 MG
Supplier: Medchemexpress LLC HY19806A5MG
Ceftolozane (CXA-101) sulfate is an antipseudomonal cephalosporin. It binds to P. aeruginosa essential PBPs (1b, 1c, 2 and 3) with high affinity and inhibits cell wall synthesis. Ceftolozane sulfate inhibits P. aeruginosa and Enterobacteriaceae.
- Antibacterial activity against fully AmpC-derepressed P. aeruginosa
- Antipseudomonal activity against carbapenem-resistant and MDR isolates
- Reduces ESBL-producing Enterobacteriaceae in neutropenic mice
- Reduces bacterial load and improves early pulmonary inflammatory response in a mice model of Pseudomonas aeruginosa acute pneumonia
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