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Medchemexpress LLC Cenisertib | 871357-89-0 | 99.9% | 50 MG

Supplier: Medchemexpress LLC HY1307250MG
Cenisertib is an ATP-competitive multi-kinase inhibitor that blocks the activity of Aurora-kinase-A/B, ABL1, AKT, STAT5, and FLT3. This inhibition leads to significant growth-inhibitory effects in neoplastic mast cells and demonstrates tumor growth suppression in xenograft models of various cancers such as pancreatic, breast, colon, ovarian, lung tumors, and leukemia.
- Mechanism of action: ATP-competitive multi-kinase inhibitor.
- Inhibits: Aurora-kinase-A/B, ABL1, AKT, STAT5, and FLT3.
- Potential applications: Induces growth inhibition in neoplastic mast cells and inhibits tumor growth in xenograft models of pancreatic, breast, colon, ovarian, lung tumors, and leukemia.
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