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Cayman Chemical CGP 71683hydrochlorIde 10mg
Supplier: Cayman Chemical 2877810 MG
An antagonist of NPY receptor Y5 (IC50 = 1.4 nM in a radioligand binding assay); selective for Y5 over Y1, Y2, and Y4 receptors (IC50s = 2,765, 7,187, and 5,637 nM, respectively); inhibits NPY-induced increases in BT-549 cell growth and MDA-MB-231 cell migration at 0.25 μM; inhibits increases in food intake induced by intracerebroventricular administration of NPY in rats at 10 mg/kg, i.p.
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