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Medchemexpress LLC CH-223191 | 301326-22-7 | 99.8% | 200 MG
Supplier: Medchemexpress LLC HY12684200MG
CH-223191 is a potent and specific antagonist of aryl hydrocarbon receptor (AhR). It inhibits TCDD-mediated nuclear translocation and DNA binding of AhR, and also inhibits TCDD-induced luciferase activity with an IC50 of 0.03 μM.
- Potent and specific antagonist of aryl hydrocarbon receptor (AhR)
- Inhibits TCDD-mediated nuclear translocation and DNA binding of AhR
- Inhibits TCDD-induced luciferase activity with an IC50 of 0.03 μM
- Inhibits TCDD-caused cytochrome P450 1A1 mRNA expression
- Suppresses cytochrome P450 1A1 expression in liver
- Reduces activity of AST and ALT
- Molecular weight: 333.39
- Molecular formula: C19H19N5O
- Appearance: solid, yellow to orange
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