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Medchemexpress LLC CH 275 | 174688-78-9 | 99.6% | 1485.77 | 1 MG
SDP

Supplier:  Medchemexpress LLC HYP12061MG

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CH 275 is a peptide analog of somatostatin that preferentially binds to somatostatin receptor 1 (sst1) with a Ki of 52 nM. It acts as a potent and selective sst1 agonist. This compound can be utilized for research related to Alzheimer's disease.

  • Potent and selective sst1 agonist (IC50=30.9 nM)
  • Binds to somatostatin receptor 1 (sst1)
  • Activates neprilysin activity in vitro
  • Decreases neprilysin/SRIF levels in App knock-in mice in vivo
  • Increases neprilysin expression and reduces Aβ plaque load in hippocampus in vivo

Catalog No. 50-004-24502


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