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Cayman Chemical ChebulagIc AcId 10mg
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Supplier:  Cayman Chemical 2520310 MG

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A polyphenol and tannin with diverse biological activities; an inhibitor of COX-1, COX-2, and 5-LO (IC50s = 15, 0.92, and 2.1 μM, respectively) as well as α-glucosidase and 15-LO (IC50s = 0.05 and 24.9 μM, respectively); inhibits LPS-induced increases in iNOS, COX-1, COX-2, and 5-LO protein levels, production of NO, PGE2, and ROS, and nuclear translocation of NF-κB in RAW 264.7 macrophages; inhibits the growth of HCT15, COLO 205, MDA-MB-231, DU145, and K562 cancer cells (GI50s = 20.3, 18, 26.2, 28.54, and 30.66 μM, respectively); increases insulin-stimulated glucose uptake in 3T3-L1 adipocytes; scavenges DPPH radicals (IC50 = 1.4 μM); exhibits antiviral activity against cytomegalovirus, hepatitis C virus, dengue virus, measles virus, and respiratory syncytial virus in vitro (EC50s = 25.5, 12.16, 13.11, 34.42, and 0.38 μM, respectively)

Catalog No. 50-293-4425


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