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Cayman Chemical CHIR99021, 252917-06-9, 5 mg

Supplier: Cayman Chemical 131225
Molecular Formula C22H18Cl2N8, Purity ≥95%, Formula Weight 465.3, Synonyms: 6-[[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile, CT 99021; An aminopyrimidine derivative that inhibits GSK3 and GSK3 (IC50s = 10 and 6.7 nM, respectively); activates glycogen synthesis in CHO-IR cells (EC50 = 0.8 M) and in isolated type 1 diabetic rat skeletal muscle; has been shown to promote self-renewal of embryonic stem cells.
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