Medchemexpress LLC Chitin synthase inhibitor 4 | 2755847-31-3 | C20H15FN4O | 5 MG

Supplier:  Medchemexpress LLC HY1506865MG

Chitin synthase inhibitor 4 (compound 4fh) is a chitin synthase inhibitor with fungicidal effect. It is a potential chitin synthase-based fungicide in agriculture.

• Shows good antifungal activities against V. mali and S. sclerotiorum with EC50 values of 0.71 and 2.47 μg/mL.
• Displays potency inhibition against V. mali and S. sclerotiorum with inhibition rates of 90.3% and 88.7% (at 50 μg/mL).
• Blocks hyphae growth, resulting in abnormal growth, decreased cell content, cell wall degradation, and plasmolysis (at 1 μg/mL).
• Exhibits inhibition against chitin synthase and polyoxin D with inhibition rates of 68.08% and 63.84% (at 50 μM; 3 h).
• Has considerable curative and protective effects against S. sclerotiorum vivo, and no obvious phytotoxicity (at 50 μg/mL).
• Has low acute toxicity, with no carcinogenic and mutagenic toxicity risk.

Catalog No. 50-003-75108