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Medchemexpress LLC Chlorpheniramine (maleate) | 113-92-8 | 99.7% | 1 ML
Supplier: Medchemexpress LLC HYB0286A10MM/1ML
Chlorpheniramine maleate, also known as Chlorphenamine maleate, is a potent histamine H1 receptor antagonist. It demonstrates an IC50 of 12 nM against the H1 receptor and has shown antimalarial activity against P. falciparum. This compound also plays a role in reducing proton currents in BV2 microglial cells and has been observed to inhibit scratching in Ovalbumin-challenged BALB/c mice.
- Acts as a histamine H1 receptor antagonist with an IC50 of 12 nM
- Exhibits antimalarial activity against P. falciparum
- Reduces proton currents in BV2 microglial cells
- Inhibits scratching in in vivo models
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