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Genscript Corporation CHO-K1/NMU1 Stable Cell Line
Supplier: Genscript Corporation M00191

Neuromedin U receptor 1 (NMUR1) is a member of G-protein coupled receptor family A and is the most abundant in peripheral tissue particularly in small intestines and stomach This protein is a receptor for Neuromedin U (NMU-25) The first biological activity ascribed to NmU was smooth muscle contraction Neuromedin U has also been reported to increase arterial blood pressure and modify ion transport in the intestinal tract Finally NmU injected subcutaneously into rats has been reported to result in a short term increase in circulating ACTH levels and a long term increase in serum corticosterone levels suggesting a role in regulation of the hypothalamo-pituitary-adrenal axis
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