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Cayman Chemical Cholesteryl Oleate 50mg

Supplier: Cayman Chemical 2647250 MG

A MC4R antagonist (Ki 0.16 UM) selective for MC4R over MC3R and MC5R (IC50s 0.32 0.81 and 2.12 UM respectively) decreases cAMP production induced by [NDP]-a-MSH by 20 in MCR4-expressing HEK293 cell membranes but has no effect on cAMP levels in MC3R- or MC5R-expressing HEK293 cell membranes at 100 UM prevents the loss of lean body mass and enhances light-phase food consumption in a LLC mouse xenograft model but does not reduce tumor size at 15 mg/kg
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