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Cayman Chemical ChondroItIn Sulfate AsodIum 5g
Supplier: Cayman Chemical 378015 G
A glycosaminoglycan; reduces LPS-induced decreases in viability, as well as LPS-induced increases in Tnf-α, Il-1β, Il-6, Ifn-γ, iNOS, and Mmp-1 levels, NO production, and NF-κB activity in primary mouse chondrocytes at 0.5 or 1 mg/ml; extracellular CSA is required for P. falciparum-infected erythrocytes to adhere to the endothelium in the brain and placenta and avoid immune detection; reduces arthritis incidence and joint swelling, decreases 8-isoprostane in articular cartilage cells, and increases IκBα levels in cartilage cell cytoplasm in a mouse model of collagen-induced arthritis at 30, 60, or 120 mg/kg per day
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