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Apexbio Technology LLC Cidofovir dihydrate 149394-66-1 10mM (in 1mL H2O)
Supplier: Apexbio Technology LLC B12385.1
Cidofovir dihydrate (CAS 149394-66-1) is a small-molecule inhibitor targeting viral DNA polymerase It is designed to selectively inhibit viral DNA synthesis thereby blocking viral DNA chain elongation and replication Cidofovir dihydrate exerts its biological activity primarily through intracellular conversion to its active diphosphate form which competitively inhibits viral DNA polymerase In cell-based studies cidofovir dihydrate demonstrates inhibitory potency against cytomegalovirus (CMV) replication typically achieving IC50 values in the low micromolar range in CMV-infected cell culture models Based on these pharmacological properties cidofovir dihydrate holds research potential in studies of antiviral efficacy virus-host interactions and antiviral resistance mechanisms
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