Medchemexpress LLC cis-4-Hydroxy-L-proline | 618-27-9 | ≥98.0% | 131.13 | 100 MG

Supplier:  Medchemexpress LLC HY40136100MG

cis-4-Hydroxy-L-proline is an orally active proline analog and collagen production inhibitor. It inhibits cell growth by preventing the deposition of triple helical collagen on the cell layer. cis-4-Hydroxy-L-proline inhibits N-nitrosomethylurea-induced breast tumor growth. cis-4-Hydroxy-L-proline improves lung compliance and reduces prostate weight. cis-4-Hydroxy-L-proline can be used in the study of hypoxic pulmonary hypertension.

• It inhibits the accumulation of collagenous and noncollagenous proteins in the culture medium in the in vitro co-culture experiment of rat Schwann cells (SC) and dorsal root ganglion neurons.
• It reduces the proportion of collagen synthesis in total protein synthesis and increases the degradation proportion of newly synthesized collagen in freshly isolated chick tendon fibroblasts.
• It significantly reduces the production of albumin and urea by hepatocytes.

Catalog No. 50-004-01575