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Selleck Chemical LLC Cl-amidine hydrochloride E4995-1MG
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Supplier:  Selleck Chemical LLC E49951MG

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Cl-amidine hydrochloride is an orally active peptidylarginine deminase (PAD) inhibitor with IC50 values of 0 8 M 6 2 M and 5 9 M for PAD1 PAD3 and PAD4 respectively Cl-amidine hydrochloride induces apoptosis in cancer cells Cl-amidine hydrochloride induces microRNA (miR)-16 (miRNA-16 microRNA-16) expression and causes cell cycle arrest Cl-Amidine hydrochloride prevents histone 3 citrullination and neutrophil extracellular trap formation and improves survival in a murine sepsis model[1][2][3][4][5]

Catalog No. 50-000-42641


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