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Cayman Chemical CL2SN38dIchloroacetIc acI 10mg
Supplier: Cayman Chemical 2821510 MG
A reactive drug-linker molecule containing SN-38 and a maleimidocaproyl linker; cytotoxic to LoVo human colon adenocarcinoma cells (IC50 = 5.3 nM) when linked to hMN-14 as an ADC; increases survival in a colon carcinoma mouse model of lung metastasis when linked to hMN-14
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