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Apexbio Technology LLC Clemizole 442-52-4 50mg
Supplier: Apexbio Technology LLC A331550
Clemizole (CAS 442-52-4) is a small-molecule antagonist targeting the histamine H1 receptor and the hepatitis C virus (HCV) NS4B protein It is designed to block the H1 receptor and disrupt NS4B-associated RNA-binding thereby inhibiting viral replication Clemizole exerts its biological activity primarily through antagonism of the H1 receptor and interference with NS4B-mediated replication processes In in vitro assays clemizole demonstrates inhibitory activity with an IC50 value of approximately 8 mM against HCV genotype 2a replication Based on these pharmacological properties clemizole holds research potential in anti-HCV therapy and related antiviral applications
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