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Medchemexpress LLC Clinafloxacin hydrochloride | 105956-99-8 | 99.6% | 100 MG
Supplier: Medchemexpress LLC HYB0536A100MG
Clinafloxacin hydrochloride is a potent and broad-spectrum fluoroquinolone antibiotic. It exhibits inhibitory activity against gram-positive, gram-negative bacteria, and anaerobic pathogens in vitro. It targets DNA gyrase and topoisomerase IV of S. aureus with IC50 values of 0.92 μg/ml and 1.62 μg/ml, respectively.
- Quinolone IC50 and target
- Active against S. pneumonia with an MIC of 1 μg/ml for parC-gyrA mutants
- Exhibits antibacterial activities against target-altered mutant strains of S. aureus
- Effective in treating penicillin-resistant, ciprofloxacin-susceptible pneumococcal meningitis in a rabbit model
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