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Abcam Clioquinol, Metal chelator and ionophore, 100MG
Supplier: Abcam AB120355100MG
MW 305.5 Da, Purity >97%. Metal chelator and ionophore with beneficial effects in animal models of neurodegenerative diseases (Alzheimer's, Parkinson's and Huntington's disease). Effects on Alzheimer's disease attributed to copper and zinc chelation or increased level of a metalloprotease. Other actions reported including iron chelation, inhibition of Huntington expression from its mRNA, proteasome inhibition when complexed with copper, and stimulation of tumor necrosis factor-α secretion. Also inhibitor of CLK-1/MCLK1 (an aging-associated protein).
The product is subject to the following: Abcam Restricted Use Statement
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