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Medchemexpress LLC Clk1-in-3 | 2922550-28-3 | 98.5% | 430.48 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY14926250MG

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CLK1-IN-3 (compound 10ad) is a potent and selective Clk1 inhibitor, with an IC50 of 5 nM and over 300-fold selectivity for Dyrk1A. It also shows a relatively potent inhibition against Clk2 and Clk4, with IC50 values of 42 and 108 nM, respectively. This compound potently induces autophagy in vitro and can be used for acute liver injury (ALI) research.

  • Potent and selective Clk1 inhibitor
  • Induces autophagy in vitro
  • Can be used for acute liver injury (ALI) research
  • Shows potential in anti-tumor applications
  • Stimulates degradation of SQSTM1/p62
  • Elevates expression level of LC3II protein

Catalog No. 50-003-60968


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