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Medchemexpress LLC Cloperastine fendizoate | 85187-37-7 | 99.53% | 5 G
Supplier: Medchemexpress LLC HYB21795G
Cloperastine fendizoate is a potassium channel inhibitor that demonstrates concentration-dependent inhibition of hERG K+ currents. It is recognized for its antitussive (cough suppressing) and antiedemic properties, in addition to its ability to relax bronchial musculature. The compound also exhibits antihistaminic effects and a papaverine-like activity.
- Inhibits hERG K+ currents with an IC50 of 27 nM.
- Possesses antitussive and antiedemic activity.
- Relaxes bronchial musculature.
- Exhibits antihistaminic and papaverine-like activity.
- Has relatively low acute toxicity when administered orally (LD50 in rats and mice exceeds 2000 mg/kg).
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