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Medchemexpress LLC HY-110143 5mg Medchemexpress, CLP257 CAS:1181081-71-9 Purity:>98%
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Supplier:  Medchemexpress LLC HY1101435MG

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Medchemexpress, HY-110143 5mg CLP257 CAS:1181081-71-9 CLP257 is a selective K+-Cl− cotransporter KCC2 activator with an EC50 of 616 nM. CLP257 is inactive against NKCC1, GABAA receptors, KCC1, KCC3 or KCC4. CLP257 restores impaired Cl− transport in neurons with diminished KCC2 activity. CLP257 alleviates hypersensitivity in rats with neuropathic pain. CLP257 modulates plasmalemmal KCC2 protein turnover post-translationally. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

Catalog No. 50-208-0779


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