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Enzo Life Sciences Cobalt (III) Protoporphyrin IX chloride, (25mg), CAS Number: 102601-60-5
Supplier: Enzo Life Sciences ALX430076M025
Heme oxygenase activator. The ability of cobalt ions to induce heme oxygenase (HO) activity in liver cells was first reported almost 30 years ago. Cobalt protoporphyrin IX (CoPP) was later shown to be a substrate for HO, now identified as the inducible isoform HO-1 (heast shock protein 32; hsp32). CoPP has been shown to down-regulate various cytochrome P450 isoforms and various mechanisms of action have been attributed to CoPP and other metalloporphyrins. Formula: C34H32CoN4O4. Cl. MW: 654.5. CAS Number: 102601-60-5. Purity: ≥95% (TLC). Appearance: Dark purple solid. Solubility: Soluble in basic aqueous solutions at pH between 8.5-9.0. Once in solution pH can be adjusted to physiological pH. Long Term Storage: -20°C
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