ABclonal Technology Complement factor D Rabbit mAb

Supplier:  ABclonal Technology A23006100UL

This gene encodes a member of the S1 or chymotrypsin family of serine peptidases This protease catalyzes the cleavage of factor B the rate-limiting step of the alternative pathway of complement activation This protein also functions as an adipokine a cell signaling protein secreted by adipocytes which regulates insulin secretion in mice Mutations in this gene underlie complement factor D deficiency which is associated with recurrent bacterial meningitis infections in human patients Alternative splicing of this gene results in multiple transcript variants At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease

Catalog No. 50-000-05285