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STEMCELL Technologies Compound E, Size: 1 mg
Supplier: STEMCELL Technologies 73954
Compound E is a potent, cell-permeable, selective inhibitor that blocks the cleavage of both gamma-secretase and the Notch intracellular domain with similar IC50 values, ranging from 0.24 to 0.37 nM (Beher et al.; Seiffert et al.). DIFFERENTIATION· Inhibits growth, differentiation, and motility of neuroblastoma cells (Ferrari-Toninelli et al.).· Accelerates the differentiation of human embryonic stem cells into primitive neural stem cells (Li et al.).
Safety and Handling
WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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