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Cayman Chemical CompstatIntrIfluoroacetate 5mg
SDP

Supplier:  Cayman Chemical 344355 MG

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A peptide inhibitor of complement activation (IC50s = 63 and 12 µM for the classical and alternative pathways, respectively); binds to C3 and inhibits convertase-mediated cleavage of C3 to C3a and C3b; inhibits the generation of C3a, activation of PMNs, and the binding of PMNs to the polymer surface in an isolated human whole blood model of extracorporeal circulation at 70 µM; inhibits the generation of C3b, C3c, and iC3b in a baboon model of heparin- and protamine-induced complement activation at 21 mg/kg

Catalog No. 50-295-0794


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