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Medchemexpress LLC Copanlisib dihydrochloride | 1402152-13-9 | C23H30Cl2N8O4 | 1 ML
Supplier: Medchemexpress LLC HY15346A10MM/1ML
Copanlisib dihydrochloride is a potent, selective, and ATP-competitive pan-class I PI3K inhibitor. It demonstrates over 2,000-fold selectivity against other lipid and protein kinases, excluding mTOR, and exhibits superior antitumor activity.
- Induces apoptosis in BT20 breast cancer cells
- Inhibits PI3K-mediated AKT phosphorylation in ELT3 cells
- Potently inhibits cell proliferation in human tumor cell lines
- Shows robust antitumor activity in athymic nude rats injected with KPL4 tumor cells
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