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Medchemexpress LLC Coumaran (2,3-Dihydrobenzofuran) | 496-16-2 | 99.5% | C8H8O | 100 G
Supplier: Medchemexpress LLC HY75247100G
Coumaran (2,3-Dihydrobenzofuran) is an AChE inhibitor that exhibits antileishmanial activity. It may develop antiparasitic abilities by activating macrophages and demonstrating immunomodulatory effects. Coumaran can also serve as a biopesticide.
- AChE inhibitor
- Antileishmanial activity
- May acquire antiparasitic capabilities through activation of macrophages
- Exerts immunomodulatory activity
- Can be used as a biopesticide
- Active against promastigote (IC50=1.042 μM) and amastigote (IC50=1.43 μM) forms
- Not significantly cytotoxic to macrophages or erythrocytes at concentrations of 0.5-13 μM over 48 hours
- Increases phagocyte and lysosomal activity and nitrite (NO2-) levels at concentrations of 0.5-13 μM over 24 hours
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