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Medchemexpress LLC CP 339818 hydrochloride | 478341-55-8 | 99.6% | 340.89 | 1 ML
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Supplier:  Medchemexpress LLC HY10857410MG

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CP 339818 hydrochloride is a non-peptide blocker of Kv1.3 (IC50 = 200 nM) and Kv1.4 channels. It also inhibits HCN channels with IC50s of 18.9 μM and 43.4 μM against HCN1 and HCN4 (high Cl-), respectively. The compound exhibits significantly weaker blocking effects on Kv1.1, Kv1.2, Kv1.5, Kv1.6, Kv3.1-4, and Kv4.2 channels. It selectively blocks Kv1.3, which in turn inhibits the activation process of human T cells. CP 339818 hydrochloride can be utilized for studying the physiological functions of HCN and Kv channels. For research use only, not for sale to patients.

  • Non-peptide blocker of Kv1.3 and Kv1.4 channels.
  • Inhibits HCN1 and HCN4 channels.
  • Selectively blocks Kv1.3, inhibiting human T-cell activation.
  • Useful for studying physiological functions of HCN and Kv channels.

Catalog No. 50-003-44762


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