Medchemexpress LLC CPD-1224 | 2891620-68-9 | C43H47ClN8O7S | 5 MG

Supplier:  Medchemexpress LLC HY1533865MG

CPD-1224 is an orally effective ALK inhibitor that is a derivative of an ALK inhibitor connected to the cereblon ligand. It targets the EML4-ALK oncogenic fusion protein, degrading both ALK and its mutant forms L1196M/G1202R. This compound has the ability to slow down tumor growth.

• Orally effective ALK inhibitor.
• Targets and degrades the EML4-ALK oncogenic fusion protein.
• Degrades mutant forms L1196M/G1202R of ALK.
• Can slow down tumor growth.
• Significantly enhances kinase binding selectivity and exhibits good degradation selectivity.
• Has 28% oral bioavailability in mice.
• Inhibits tumor growth in mice at a dosage of 10 mg/kg, orally, twice daily for 15 days.

Catalog No. 50-003-73310