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Medchemexpress LLC CPPHA | 693288-97-0 | 98.1% | 406.82 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY14612100MG

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CPPHA is a potent and selective positive allosteric modulator (PAM) of the mGluR5 and mGluR1 (metabotropic glutamate receptor). It can potentiate responses of mGluR5 and mGluR1 to the activation of these receptors and is developed for the research of central nervous system disorders.

  • Potentiates responses of mGluR5 and mGluR1 to activation
  • Causes concentration-dependent potentiation of human mGluR5 CHO cells to agonists
  • Potentiates threshold response to glutamate in fluorometric Ca2+ assays
  • Potentiates DHPG-induced increase in phosphorylation of ERK and CREB

Catalog No. 50-003-59824


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