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Medchemexpress LLC Crbn-6-5-5-vhl | 2362575-45-7 | MFCD32705129 | 99.5% | 972.20 | C51H69N7O10S | 5 MG
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Supplier:  Medchemexpress LLC HY1362625MG

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CRBN-6-5-5-VHL is a VHL-based proteolysis targeting chimera (PROTAC) for research use that induces selective degradation of cereblon (CRBN) in cellular assays. It demonstrates potent degradation activity (DC50 = 1.5 nM) with minimal effect on common neo-substrates, making it suitable for mechanism-of-action and targeted protein degradation studies.

  • Potent cereblon degradation (DC50 = 1.5 nM).
  • Selective activity with little effect on IKZF1 and IKZF3.
  • High reported purity (99.45%).
  • Suitable for in vitro and cellular degradation assays.
  • Available in small-scale research quantities (e.g., 5 mg).

Catalog No. 50-002-22108


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