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Selleck Chemical LLC Crenolanib (CP-868596) 5mg 670220-88-9 ARO 002
SDP

Supplier:  Selleck Chemical LLC S27305MG

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Crenolanib (CP-868596, ARO 002) is a potent and selective inhibitor of PDGFR?/? with Kd of 2.1 nM/3.2 nM in CHO cells, also potently inhibits FLT3, sensitive to D842V mutation not V561D mutation, >100-fold more selective for PDGFR than c-Kit, VEGFR-2, TIE-2, FGFR-2, EGFR, erbB2, and Src. Crenolanib helps to induce mitophagy. *For Research & Development use only.  Product is not intended for drug, household, or human consumption.

Catalog No. NC0623788


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