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Selleck Chemical LLC Crizotinib S1068-1g
Supplier: Selleck Chemical LLC S10681G
Crizotinib is a potent inhibitor of c-Met and ALK with IC50 of 11 nM and 24 nM in cell-based assays respectively It is also a potent ROS1 inhibitor with Ki value less than 0 025 nM Crizotinib induces autophagy through inhibition of the STAT3 pathway in multiple lung cancer cell lines
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