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Cayman Chemical Crotonosde 5mg

Supplier: Cayman Chemical 282195 MG

A potent agonist of GPR35 (EC50 1 61 nM) inhibits histamine release in isolated rat peritoneal mast cells (IC50s 0 1-50 UM) inhibits A23187-induced calcium influx in isolated rat mast cells reduces antigen-induced histamine release from rat conjunctival tissue by 46 in vitro when used at a concentration of 10 Ug/ml dose-dependently reduces the immediate hypersensitivity response in rat conjunctiva in vivo reduces mast cell degranulation in rat conjunctiva
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