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Medchemexpress LLC Crotonyl-CoA tetrasodium | 992-67-6 | 97.85% | C25H36N7Na4O17P3S | 1 MG
Supplier: Medchemexpress LLC HY141466A1MG
Crotonyl-CoA is a high-energy acyl donor and an intermediate in the fermentation of butyric acid, as well as in the metabolism of lysine and tryptophan. It is crucial in the metabolism of fatty acids and amino acids. This stable tetrasodium salt form retains the same biological activity as the free acid.
- Acts as a substrate for p300's histone crotonyltransferase activity
- Regulates global and gene-specific histone crotonylation levels in cells
- Can be utilized for research on LPS-induced inflammatory responses
- Directly stimulates transcription in a cell-free system
- Increases global H3K18Cr levels in HeLa S3 cells
- Enhances H3K18Cr at de novo-activated gene promoters in RAW 264.7 cells
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