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FUJIFILM BIOSCIENCES INC CultureSure A-83-01
Supplier: FUJIFILM BIOSCIENCES INC 03924111
CultureSure A-83-01 is a selective inhibitor of TGF-b type II/activin receptor-like kinase ALK5 type I activin/nodal receptor-like kinase ALK4 and type I nodal receptor-like kinase ALK7 It inhibits Smad2/3 phosphorylation and inhibits TGF-b induced epithelial to mesenchymal transformation It exerts almost no effect on bone morphogenetic protein type I receptor p38 MAP kinase and extracellular signal-regulated kinase Furthermore it has been reported that when added to rat iPS cell culture medium it facilitates uniform growth of rat iPS cells without differentiation and can be cultivated over a long period Li W Cell 4 16 2009
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