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Medchemexpress LLC Cyclo(Arg-Gly-Asp-D-Phe-Cys) (Cyclo(RGDfC)) | 862772-11-0 | 98.1% | 578.64 | 5 MG
SDP

Supplier:  Medchemexpress LLC HYP23005MG

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Cyclo(Arg-Gly-Asp-D-Phe-Cys) (Cyclo RGDfC) is a cyclic RGD peptide with high affinity to αvβ3, capable of disrupting cell integrin interactions. It inhibits pluripotent marker expression in embryonic stem cells (ESCs) and the tumorigenic potential of mESCs in vivo.

  • High affinity to αvβ3
  • Disrupts cell integrin interactions
  • Inhibits pluripotent marker expression in embryonic stem cells
  • Inhibits tumorigenic potential of mESCs in vivo
  • Down-regulates transcription factors Oct 4, Sox 2, and Nanog in mESCs
  • Inhibits integrin gene expression in mESC-col I constructs
  • Promotes aggregate formation and detachment in mESCs
  • Applicable in tumor research

Catalog No. 50-004-23918


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