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Medchemexpress LLC Cyclo(CKLIIF) (TFA) | 98.1% | 831.99 | 5 MG
Supplier: Medchemexpress LLC HYP10221A5MG
Cyclo(CKLIIF) TFA is a dual inhibitor for hypoxia inducible factor (HIF) 1 and 2. It functions by disrupting the interaction of both HIF1-α and HIF2-α with HIF1-β, exhibiting an affinity (KD) for HIF1-α and HIF2-α PAS-B domains of 2.6 μM and 2.2 μM, respectively. This product is suitable for use as a laboratory chemical in the manufacture of substances.
- Dual inhibitor for HIF 1 and 2
- Disrupts interaction of HIF1-α and HIF2-α with HIF1-β
- Affinity for HIF1-α PAS-B domain is 2.6 μM
- Affinity for HIF2-α PAS-B domain is 2.2 μM
- Molecular weight: 831.99
- Appearance: White to off-white solid
- Soluble in DMSO at 100 mg/mL
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