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Apexbio Technology LLC Cyclopiazonic acid 18172-33-3 10mg
Supplier: Apexbio Technology LLC B664710
Cyclopiazonic acid (CAS 18172-33-3) is a neurotoxic secondary metabolite produced by Aspergillus flavus It acts as a potent nanomolar inhibitor of the sarco/endoplasmic reticulum Ca -ATPase (SERCA) selectively targeting this calcium pump with minimal activity against other membrane-bound ATPases Cyclopiazonic acid has been shown to inhibit SERCA function in intact tissues cultured endothelial cells smooth muscle preparations and plant systems It is frequently employed in research to study calcium signaling endoplasmic reticulum calcium homeostasis and pathophysiological processes such as cell death induction and vascular responses
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