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Apexbio Technology LLC CYM 5442 1094042-01-9 25mg
Supplier: Apexbio Technology LLC B744125
CYM 5442 (CAS 1094042-01-9) is a highly selective agonist of the sphingosine-1-phosphate receptor 1 (S1P1) exhibiting an EC50 of 1 35 nM and demonstrating no activity toward other S1P receptor subtypes By specifically activating S1P1 CYM 5442 promotes phosphorylation of p42/p44-MAPK signaling pathways The compound shows effective central nervous system penetration and has been utilized in studies investigating neuroprotection particularly in retinal neuronal models Its selectivity and defined mechanism have made it valuable for dissecting S1P1-mediated signaling in neurobiological research contexts
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